Novel Nomograms-Based Prediction Models for Patients with Primary Undifferentiated Pleomorphic Sarcomas Resections
نویسندگان
چکیده
منابع مشابه
Head and Neck Tumors: Management of Primary Undifferentiated Pleomorphic Sarcoma
Introduction: Sarcomas account for 1% of all tumors originated in the head and neck regions in adults. They constitute a heterogeneous group of tumors of mesenchymal origin with multiple histological variants. The undifferentiated pleomorphic sarcoma (UPS) subtype is the most frequent variant with an incidence range of 2.7-38%. Materials and Methods: This retrospective...
متن کاملPrimary undifferentiated pleomorphic sarcoma of the thyroid
RATIONALE Primary undifferentiated pleomorphic sarcoma is extremely rare in the thyroid, and can be easily misdiagnosed as anaplastic thyroid cancer. PATIENT CONCERNS We present a case of a 71-year-old woman who presented with a rapidly growing painless mass in the neck. DIAGNOSES-INTERVENTIONS-OUTCOMES Computed tomography showed a large hypointense mass with hyperdense areas involving whol...
متن کاملCopy number alteration signature defines undifferentiated pleomorphic sarcomas and leiomyosarcomas with poor prognosis
Results LMS presented lower frequency of genomic alterations in comparison with UPS. None of the variables were identified as independent prognostic factors, but gains at 1q21.3 were significantly associated with poor survival and showed almost significance as an independent prognostic factor (relative risk 13.8, P = 0.019). In addition, copy number profile of UPS and LMS was indistinguishable ...
متن کاملAre peripheral purely undifferentiated pleomorphic sarcomas with MDM2 amplification dedifferentiated liposarcomas?
Dedifferentiated liposarcoma (DDLPS) has been defined as a tumor composed of well-differentiated liposarcoma associated with a nonlipogenic undifferentiated sarcoma and is genetically characterized by a 12q13-15 amplicon with MDM2 amplification. Some peripheral (extremities, trunk wall, head/neck) undifferentiated pleomorphic sarcomas (UPS) without areas of well-differentiated liposarcoma prese...
متن کاملUndifferentiated pleomorphic sarcoma*
Dear Editor, By definition, sarcomas are malignant tumors of tissues, derived from mesoderm and involve the oncogenic transformation of mesenchymal stem cells. The two main types of sarcoma are bone and soft tissue sarcomas. Soft tissue sarcomas generally manifest as deep lesions, but they may affect the skin and subcutaneous tissue.1 They are grouped according to similarities in their clinical...
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ژورنال
عنوان ژورنال: Cancers
سال: 2021
ISSN: 2072-6694
DOI: 10.3390/cancers13081917